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Doraemon and Nobita were using special shoes that allows them to jump into the worlds of the books that they want. Nobita let Shizuka use those shoes to enter the world of the book that she wants. Shizuka got lost in one Nobita's Sinbad Legend of the Seven Seas book. After Nobita's mother burned all of his books, Doraemon and the others must find another way to save Shizuka.

Tired of the daily life and being the weakest, slowest, and dumbest, Nobita seeks comfort in his dreams where, using Doraemon's tools, he sets out on a fantasy journey. But when Nobita's dream world gets threatened by an evil sorcerer, Nobita gathers his friends to join him in his dream to fight the evil as the Three Musketeers.

Nobita had to find a topic for his summer break research homework. As he was blaming everything to Adam and Eve for sinning and causing their descendants to suffer (from homework), Doraemon decided to provide him with a gadget to observe the creation of the world so that he may write it in a diary-like report. Suneo, Giant and Shizuka eventually joined them and together they watch over the birth of tribes and civilizations. Meanwhile, the time patrol is looking for an illegal time machine whose controllers accidentally heard Giant speaking of the genesis diary project. They captured Giant and Suneo; leaving Nobita, Shizuka and Doraemon to watch over the genesis set and to rescue them.

The kids go on a space Mystery Train bound for a space theme park, when a race of alien virus strikes, wanting to take them as host bodies.

After Suneo bragged about having a ranch, Nobita was asked whether or not he has one, pressuring him to say yes. Doraemon won a number of lotteries for useless planets in the belt between Mars and Jupiter. When Suneo and the rest came to see the ranch, Nobita happened to read the last of the lottery number to the go-anywhere-door, leading them to a huge dreamlike area. As Nobita's toy horse pranced around because of the wind-up life gadget, Suneo and the others became interested in doing the same to their toys and let them live in the area. So they decided to make their own clockwork city.

After bragging about receiving a space trip ticket from his father, Suneo concedes they would have to wait quite a while until they can actually go. So, Nobita and co. turns to Doraemon for it, but they were given a space simulation game to play together instead. Unfortunately an accident with another gadget occurred, leaving Suneo and Giant trapped inside the game, only to be picked up by someone from outer space. Nobita, Shizuka and Doraemon then pursued the UFO that has the game inside it which took them all to a real space adventure.

Nobita and his friends gathered at Shizuka's house when they heard about the news about missing flocks of bird species. Nobita believed they were taken away by winged creatures and became obsessed on flying on his own. He created mechanical wings and upon the experiment he encountered an actual winged creature flying out of a time-space distortion. Upon helping him whose name is Gusuke, Nobita and his friends were sucked into the distortion and reached Gusuke's home, Birdpia or the world where the winged creatures live.

One day, Nobita finds a stray dog drowning in a river while playing by the river side. Feeling sorry for the dog, he decides to take it home by hiding it in a "kennel on the wall" and names it Ichi (originated from "One", which sounds similar to "wan", the sound a dog makes according to the Japanese language), and secretly feeds it and plays with Ichi with his Kendama to find. Soon after, he also adopts a stray cat named Zubu (or wet in Japanese, due to the discovery of it in a rainstorm)... and many other stray cats and dogs. With so many stray cats and dogs, Nobita, along with his friends, decide to send them back in time, 300 million years ago, where there was no other living beings around. After using the Ray of Evolution to allow them to operate a food-making machine, they depart, with a promise to return to the present. However, when they try to visit them the next day (from their point of view), they encountered a time-space anomaly, sending them crash landing 1,000 years before their original time-destination— to their surprise, They found out the dogs and cats have evolved enough to form a civilized society that rivaled those of Future Society. As the time machine is broken, they try to find help to repair it so they can continue their chrono-journey, only to learn of a bigger issue — a cluster of asteroids are going to Collide with Earth. Will Nobita finally reunite with Ichi, as he promised? More over, what's with Hachi, a dog who resembles Ichi greatly? The 300 million years of time and space adventure begins.

Nobita finds a fossilized dinosaur egg by accident, and with the help of Doraemon's tools, they hatched the egg and began raising the dinosaur. Knowing that they can't keep the dinosaur forever, Nobita was forced to send it back to prehistoric times where a group of hunters from the future threatens to endanger the dinosaurs. Determined to save the dinosaurs from the claws of the hunters, Doraemon and the gang returns to the past and sets out in a prehistoric adventure.

Nobita requests of Doraemon the Moshimo-box and wishes for the world to become a place where the use of magic is possible. Witchcraft replaces science and technology and everyone makes use of it on their daily lives, except for Nobita, who, like usual, isn't very good at conjuring spells. Frustrated, he plans on returning things to their past state, but his mother threw the Moshimo-box away. One day, Doraemon and his friends meet Professor Mangetsu, who studies magic and magical beings such as goblins, and his daughter Miyoko, and are warned of the dangerous approximation of the "star of the Underworld" to the Earth's orbit. With the future of the planet at stake, the group must travel to the Underworld and pierce the heart of the Underworld King with a silver dart, as detailed in the ancient texts of "The Chronicles of the Underworld". Their attempts are, however, thwarted and Miyoko captured. Doraemon and his friends then decided to use the Time Machine to return to the past and, using Dorami's Moshimo-box, they manage to restore the Earth. The events on the Underworld continue, however, to take place in a Parallel Universe, where Miyoko is still captive. As a result, the group is once again forced to travel to the Underworld and defeat its tyrannical ruler once and for all.

Nobita and his dad buy a big rhinoceros beetle, which he promises to his dad to take good care of it. Later, Doraemon's group finds a strange island where a tribe co-exists with prehistoric creatures long believed to extinct yet preserved by a mythical beetle spirit named Golden Hercules. However, the group has to deal with a group of criminals from the future who intend to capture Golden Hercules for a profit.